Fighting Cancer Innovators – New Jersey Business Magazine


Often times over the years it seemed that the cure was there worse than the disease in treating cancer. Patients feared that the treatment would result in permanent side effects that impaired their quality of life and functionality.

Today, New Jersey hospitals are at the forefront of the emerging fight against cancerTechnologies that enable doctors to extend patient lives. Improved screening technologies for early detection and treatment target tumors more accurately and kill cancer cells with less risk of damaging surrounding tissues and organs.

Improved Technologies are critical to keeping pace with the spread of cancer in the US, the incidence of which is set to increase by about 45% over the next 20 years, said Dr. Andre Goy, chairman and chief executive officer of John Dearer Hackensack University Cancer CenterMedical center of the city. Goy notes that there are 4,950 new cancer cases reported In the United States, more than 1,700 people die of cancer every day.

Doctors diagnose a new patient every 30 seconds and every three Protocol, Two people die of cancer in the United States. Part of tThis is because life expectancy is longer, but almost half of the cancers diagnosed are due to lifestyle factors such as poor diet, sedentary lifestyle, smoking, and alcohol.

“Cancer is the result of the accidental accumulation of genetic errors called mutations that didestroy the cells, which eventually leads to cancer cells, “says Dr. Goy. Doctors at the John Dearer The Cancer Center uses a form of immunotherapy known as T-cell therapy to reactivate T-cells to fight cancer cells. T cells are a type of white blood cell that develops made from stem cells in the bone marrow and are essential for the immune system to fight disease.

“The goal of immunotherapy is to restore the immune system’s natural ability to kill cancer cells: one of the most efficient immunotherapies is called T-cell Interventional therapies, ”says Goy. A therapy, CAR-T-cell therapy or CART, allows doctors to take a patient’s own T cells and recharge them by manipulating them in the lab to kill cancer cells. “We started the CART program here nine years ago. We were toohe is the first to have a CART program in New Jersey and we are the largest CART program in the tri-state area alongside Sloan Kettering, ”he says.

In August 2017, the Food & Drug Administration co-approved CART for the treatment of aggressive B-cell leukemiapsed or distributed. A few months later, it approved use for aggressive B-cell lymphoma for those who had relapsed or unresponsive to other treatments.

“After four years, around 40% of patients with aggressive lymphoma are doing well with CART without disease – and probably cured – which is unprecedented, ”says Goy. Since then, the FDA has approved CART for other types of lymphoma, including mantle cell lymphoma, which is a rare but often chemoresistant cancer. “

John Dearer Doctors use other forms as wells T-cell therapy, including one that works through checkpoint inhibitors that unleash the immune system to attack the cancer. “This approach has and changes cancer in almost every organ,” says Goy. “Not just melanoma and lung cancer, where possible”revolutionized treatment, but also bladder, colon, breast, head and neck cancer.

“It’s important to understand that the benefit of T-Cell Engagement Therapy is that it is a one-time treatment – once the immune system is reactivated, it continues.” to work indefinitely, ”says Goy.


Proton therapy, in which doctors can precisely apply the entire dose to the cancer without damaging any other organs, has become widely used as a treatmentt with less impact on the patient’s quality of life.

“Proton therapy is used in the treatment of brain tumors, head and neck tumors, breast, lung and stomach tumors in the upper abdomen, pancreatic cancer, gynecological cancers and other cancers and hematological diseasesAlignments such as lymphomas, ”reports Dr. Rahul R. Parikh, radiation oncologist at the Rutgers Cancer Institute of New Jersey and medical director of the Laurie Proton Therapy Center at Robert Wood Johnson University Hospital in New Brunswick. “The data areIt is becoming more and more convincing that proton treatment can be superior to standard X-ray therapy. “

Doctors have demonstrated the benefits of proton therapy for breast cancers such as lung and breast cancers. It is not a substitute for chemotherapy or radiation or surgery in the treatment of breast cancer, Parikh notes that proton therapy has less of an impact on the heart and lungs, which are sometimes damaged by chemotherapy or standard radiation.

Doctors are being persecuted at Valley-Mount Sinai Comprehensive Cancer Care in ParamusKing with the patient’s movements ExacTrac Dynamic body movement tracking technology. The technology, which has been expanded to include surface tracking, records images of the patient’s body surface in order to show movements during the treatment.


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